Prostate Cancer Vaccine Frequently Asked Questions. How it works Dosage Treatment Video

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Vaccine Frequently Asked Questions

What is a prostate cancer vaccine?

The vaccine is a prescription medicine that is used to treat some patients with advanced prostate gland cancer. It is made from your own immune cells. It has been approved by the US Food and Drug Administration (FDA) as an autologous cellular immunotherapy for the prevention treatment of asymptomatic or minimally symptomatic metastatic castrate resistant (hormone refractory) prostate cancer.

How does the vaccine work?

The precise chemical process of action of the vaccine is not known,

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The vaccine is designed to make it possible for the immune system to find and zero in prostate cancer cells. The dosage handling of the vaccine is made specifically for the individual patient. Treatment begins with accumulation of the patient’s immune cells through a cell collection procedure called leukapheresis. These cells are then shipped to the medicine manufacturing unit where they are processed with a recombinant protein. The recombinant protein helps to activate the immune system and functions as a prostate cancer associated antigen, which may make it possible for the immune system to target and attack the prostate cancer cells in the body. It also works as an immune cell activator. Once completed, the activated cells are infused into the patient. Inside the human body of men, the vaccine is made to stimulate an immune response to prostate cancer.

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What does the vaccine do?

The vaccine's goal is to produce an immune response to prostate gland cancer.

What's the side effects?

The most common side effects include chills, fatigue, fever, back pain, nausea, joint ache, and headache.
Continue to vaccine side effects...

What should I tell my doctor before receiving the vaccine?

He should be made aware about all your medical problems, including heart and lung problems, or a history of stroke. He should know about all the drugs you take, including prescription drugs and nonprescription drugs, vitamins, herbal and dietary supplements.

What is the vaccine's dose treatment therapy?

Treatment with the vaccine involves 3 doses given approximately 2 weeks apart. The total course of treatment therapy with the vaccine can be completed in approximately 1 month. Each dose of the vaccine is given intravenously and takes approximately 60 minutes to infuse. Before receiving a dose of the vaccine, a patient may be given an acetaminophen, such as Tylenol®, and an antihistamine such as Benadryl®, orally, to reduce the potential for side effects. Each infusion is preceded by a leukapheresis procedure. After 3 doses, no further treatment with the vaccine is required.

What is leukapheresis?

Since the vaccine is made from your immune cells, your cells will be gathered approximately 3 days before each scheduled infusion of the vaccine. You will need to go to a cell collection center for this collection procedure. The collection is called leukapheresis (pronounced loo-kuh-fuh-REE-sis). For this procedure, a small tube (catheter) will be placed into veins in each arm or in a vein in your upper chest or neck. Once the procedure begins, blood will flow from your vein into a machine where the blood is divided into various components. The immune cells (along with some of the platelets and a small amount of red blood cells) are removed. The rest of the cells and the plasma are returned to your body.

A leukapheresis process can last from 3 to 4 hours. What are the possible vaccine side effects of the leukapheresis process? Side effects following a leukapheresis process are not common, but can include tingling in the fingers and around the mouth, dizziness, feeling light-headed, nausea, and feeling cold.

If you have poor venous access, you may need to have an in-dwelling catheter (a thin tube placed into a large vein for a period of time) to collect the immune cells. In Study 1, 23.0% of patients needed an in-dwelling catheter. Contamination of venous catheters can result in infections, which may interrupt your treatment with the vaccine and cause additional complications that lead to serious injury, hospitalization, or death. Symptoms of infections could include fever and redness or pain at the catheter site. These symptoms should be reported to your health care provider immediately. If you experience an unexplained fever, you should contact your health care provider and seek emergency care.

Where can I get the vaccine?

Within the first year of FDA vaccine approval, the manufacture anticipates being able to produce the vaccine to support the treatment of about 2,000 patients. At launch, treatment will be available through approximately 50 centers across the country previously approved as clinical trial sites. As the manufacturing capacity increases over the next 12 months, the vaccine will become more broadly available. For further information about the vaccine, ask your doctor. The doctor who provides most of the care for your prostate cancer is the best person to discuss treatment health options with you.

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Prostate Cancer Questions and Answers

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Love Making Following Prostate Cancer
Simply put, impotence healing from prostate cancer is physical therapy that heals on both a physical and emotional plain. If sex is still a struggle...hang on and keep trying. It may never be what it was, but in most cases you can recover potency from prostate cancer.

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